State of enteral parallel microbiota in chronic duodenal insuffi ciency

Objective . To study the state of enteral parietal microbiota and to assess conjugacy its changes with motor-evacuation disorder gastrointestinal tract (gastrointestinal tract) in chronic duodenal insufficiency. Materials methods The included 40 patients insufficiency (CDN). Of these, 21 (52.5%) were women, 19 (47.5%) men, average age was 37.1± 13.8 years. CDN diagnosed using anamnestic physical data, X-ray endoscopic examinations, intracavitary manometry. Enzyme immunoassay determined vitamin B12, 25-OH Vitamin D, transferrin. motor function carried out gastroenteromonitor “Gastroscan-GEM”. method gas chromatography mass spectrometry used wall microbiota. results blood showed a decrease fat-soluble vitamins B12 D relation control. There transferrin saturation coefficient (13.2%) compared control group (34.7%, p=0.04). Gastroenteromonitoring on device “Gastroscan-GEM” coefficients rhythmicity stomach DPC fasting postprandial periods. Chromass spectrometric analysis resident microflora revealed significant Lactobacillus spp 1245.3± 0.21 cl/g x 10^3 Bifidobacterium 1453.2± 0.18cl/g against background pronounced growth bacteria genus Clostridium, Eggerthella lenta 412.3± 0.84cl/g 10^3, Propionibacterium acnes 58.6± 0.32cl /g freudenreichii 2388.7± 0.62 jenseni 146.6±0.32 Staphylococcus 658.4± 0.28 Streptococcus mutans (anaerobic) 494.3±0.74 Streptomyces spp. 305.3±0.26 10^3. It shown that increased pathogenic associated violation rhythm motility. Conclusion In insufficiency, detected, depending activity duodenum.